@article{Gaboury_Dobkin_Roberge_Beaulieu_Dagenais_Gervais_Roux_Boire_2020, title={Mindfulness-Based Reduction Stress Reduction for Patients with Rheumatoid Arthritis and Depressive Symptoms: a Pilot Trial}, volume={7}, url={https://ijwpc.mcgill.ca/article/view/210}, DOI={10.26443/ijwpc.v7i1.210}, abstractNote={<p>Background : Despite their efficacy at controlling joint inflammation, current treatments of rheumatoid arthritis (RA) leave up to 40% of patients into non-remission. Non-remission, frequently due to persistently negative self-reported impact of RA, was found to be associated with significant persistent depressive symptoms 6-7 months after initiation of arthritis treatment. Mindfulness-Based Stress Reduction (MBSR) is proposed to improve depressive symptoms and RA-related clinical outcomes. To pave the way for an eventual randomized controlled trial, a feasibility and acceptability study of MBSR has been realized.</p><p> </p><p>Methods: A standardized 8-week MBSR program was offered to groups of patients with controlled inflammatory disease but high levels of depressive symptoms.</p><p>Qualitative interviews based on a theoretical framework of acceptability were conducted. Change in depressive symptoms (CES-D tool), fatigue and pain (SF-36), anxiety (GAD-7), pain, disease activity (PtVAS and SDAI scores) was measured over a 6-month period.</p><p> </p><p>Results: 27 patients have been recruited (3 distinct MBSR groups). Factors leading to a higher rate of success in recruitment were identified. Despite the small sample, the intervention was found to have a clear impact on depressive symptoms (p=0.004), anxiety (p=0.005), and social functioning (from the SF-36; p=0.04). Patients reported that MBSR gave them the opportunity to control their reactions in face of stressful situations.</p><p>Perceptions were almost uniformly positive towards MBSR, and most appear to have integrated some part of the intervention in their daily life.</p><p> </p><p>Conclusions: Although recruitment was challenging, a MBSR trial on depressed patients with controlled inflammatory disease was found acceptable and feasible within this population. Preliminary clinical results showed positive impacts of such intervention.</p><p> </p><p> </p>}, number={1}, journal={The International Journal of Whole Person Care}, author={Gaboury, Isabelle and Dobkin, Patricia and Roberge, Pasquale and Beaulieu, Marie-Claude and Dagenais, Pierre and Gervais, France and Roux, Sophie and Boire, Gilles}, year={2020}, month={Jan.}, pages={7–8} }